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1,3-Dipolar cycloaddition of unstabilized N-methyl azomethine ylide to nitrobenzene annelated with azoles

✍ Scribed by Alexey M. Starosotnikov; Maxim A. Bastrakov; Sergey Yu. Pechenkin; Margarita A. Leontieva; Vadim V. Kachala; Svyatoslav A. Shevelev


Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
124 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The 1,3‐dipolar cycloaddition of unstabilized N‐methyl azomethine ylide to mononitro benzazoles was studied. Depending on the nature of substituents and annelated azoles, the reaction affords previously unknown isoindole fused heterocyclic systems. The reactivity of the cycloadducts was examined. J. Heterocyclic Chem., (2011).


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Double 1,3-dipolar cycloaddition of N-me
✍ Maxim A. Bastrakov; Alexey M. Starosotnikov; Sergey Yu. Pechenkin; Vadim V. Kach πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 229 KB

## Abstract magnified image The 1,3‐dipolar cycloaddition of unstabilized azomethine ylide **1** with meta‐dinitrobenzene fused with nitrogen heterocycles affords the corresponding decahydropyrrolo[3,4‐__e__]isoindole cycloadducts in good yields. This is a first example of [3+2]‐cycloaddition of a