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1,3-Dipolar cycloaddition in the synthesis of pyrazolyl-substituted nitronyl nitroxides

✍ Scribed by E. V. Tretyakov; S. E. Tolstikov; G. V. Romanenko; Yu. G. Shvedenkov; R. Z. Sagdeev; V. I. Ovcharenko

Book ID
106519882
Publisher
Springer
Year
2005
Tongue
English
Weight
693 KB
Volume
54
Category
Article
ISSN
1573-9171

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A convergent synthesis of substituted py
A convergent synthesis of substituted pyrrolidines by 1,3 dipolar cycloaddition
✍ George A. Kraus; Jon O. Nagy πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 184 KB

Thiazolium ylids 2a and 2b are converted to 4 in 3 steps. Summary: The 1,3-dipolar cycloaddition of azomethine ylids with activated alkenes constitutes an effective synthetic method for certain pyrrolidines. 1 However, the reaction is rather limited in that R and R' are invariably aryl substituents