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Synthesis of 3-thienyl substituted 2-pyrazolines by 1,3-dipolar cycloaddition

โœ Scribed by M. M. Krayushkin; M. A. Kalik; S. A. Voznesensky


Book ID
112387368
Publisher
Springer
Year
1994
Tongue
English
Weight
320 KB
Volume
43
Category
Article
ISSN
1573-9171

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Thiazolium ylids 2a and 2b are converted to 4 in 3 steps. Summary: The 1,3-dipolar cycloaddition of azomethine ylids with activated alkenes constitutes an effective synthetic method for certain pyrrolidines. 1 However, the reaction is rather limited in that R and R' are invariably aryl substituents