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1,3-cyclohexanedione as the precursor of C4X-C6-C4Y systems. Synthesis of pyrrolo[2,3-e]indoles and thieno[2,3-e]indoles

✍ Scribed by Roberto Martínez; Juan Sandoval Oloarte; Gustavo Avila

Publisher: Journal of Heterocyclic Chemistry
Year: 1998
Tongue: English
Weight: 370 KB
Volume: 35
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570350315

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✦ Synopsis

Abstract

A novel synthesis of substituted pyrrolo[2,3‐e]indoles and thieno[2,3‐e]indoles is described. This new approach uses 1,3‐cyclohexanedione as the starting material. Diketone intermediates are obtained in four steps from the aforementioned ketone. Using these intermediates, the title compounds are synthesized efficiently.

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