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[125I]iodopride: a specific high affinity radioligand for labelling striatal dopamine D-2 receptors

โœ Scribed by Aaron Janowsky; Tomas De Paulis; Jeffrey A. Clanton; Howard E. Smith; Michael H. Ebert; Robert M. Kessler


Book ID
115881972
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
167 KB
Volume
150
Category
Article
ISSN
0014-2999

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We have prepared (S)-5-chloro-3-[ 1251]iodo-2-methoxy-N-( l-azabicyclo[2.2.2]oct-3-yl)benzamide ([125I]DAIZAC, [ 1254-3) as a radioligand for characterization of the 5-HT-3 receptor. Preparation of the 3-tri-n-butylstannyl precursor was accomplished from the corresponding unlabeled DAIZAC by reactio