[125I] 3-quinuclidinyl 4-iodobenzilate: A high affinity, high specific activity radioligand for the M1 and M2-acetylcholine receptors
β Scribed by Raymond E. Gibson; Waclaw J. Rzeszotarski; Elaine M. Jagoda; Barbara E. Francis; Richard C. Reba; William C. Eckelman
- Book ID
- 118340344
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 511 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0024-3205
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π SIMILAR VOLUMES
We have prepared (S)-5-chloro-3-[ 1251]iodo-2-methoxy-N-( l-azabicyclo[2.2.2]oct-3-yl)benzamide ([125I]DAIZAC, [ 1254-3) as a radioligand for characterization of the 5-HT-3 receptor. Preparation of the 3-tri-n-butylstannyl precursor was accomplished from the corresponding unlabeled DAIZAC by reactio
## Abstract 6βChloroβ3β((2β(__S__)βazetidinyl)methoxy)β5β((__E__)β2β(2β[^18^F]fluoropyridinβ4βyl)vinyl)pyridine ([^18^F]NIDA 52289), a very high affinity radioligand for studying nicotinic acetylcholine receptors (nAChRs) by positronβemission tomography, was synthesized through Kryptofix 222 assist