## SUmARY We have examined the labelling of [1231] HIBG by a Cu(1) catalyzed reaction in aqueous solution. We regularly obtained >99% radiochemical purity [1231] MIBG product and >97% radiochemical yield. At 100Β°C with 2 mg MIBG the radiochemical purity reached 85% at 2.5 Pin, 97% at 5 min and 99%
123I-labelling of iodophenylalanine derivatives
β Scribed by Peter Gielow
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 174 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0020-708X
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π SIMILAR VOLUMES
## Synthetic routes to D-giucose derivatives labelled = 1.6 hr) = 56 hr) and with either the positron emitter 75Br or the single photon emitters 77Br 123 I (T1/2 13.3 hr) in positions 2 or 3 were investigated in order to prepare useful tracers for glucose utilization studies in brain and heart.
The syntheres of two analogues of lowdensity lipoprotein (LDL) labelled with 123i Rabbit LDL was employed or l3'I was optimized for radbpharmaceutlcal application. due to its uoefulness in pre-cliniml experimentation, although the parameters which were optlmlzed also pertain to human LDL. LDL was i