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1,2-Dithiolan-3-ones and derivatives structurally related to leinamycin. Synthesis and biological evaluation

✍ Scribed by Raul Salvetti; Giovanni Martinetti; Daniela Ubiali; Massimo Pregnolato; Giuseppe Pagani


Book ID
114019252
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
195 KB
Volume
58
Category
Article
ISSN
0014-827X

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## Abstract A series of new 1‐, 2‐ and 3‐piperazinylbenzothieno[2,3‐__d__]triazole derivatives structurally related to Trazodone were prepared and tested for their antiserotonergic, antiadrenergic and antihistaminergic __in vitro__ activities together with their analgesic __in vivo__ activity by us