A facile synthesis of (S)-(−)-7,8-difluo
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Soon Bang Kang; Eu Jin Ahn; Youseung Kim; Yong Hae Kim
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Article
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1996
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Elsevier Science
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French
⚖ 217 KB
A convenient procedure for preparation of the title compound of->99% ee starting from 1-(2,3-difluoro-6-nitrophenoxy)-2-propanone (3) is presented. The key reaction is the intramolecular cyclization reaction in the presence of zinc chloride.