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[11C]-MeJDTic: a novel radioligand for κ-opioid receptor positron emission tomography imaging

✍ Scribed by Géraldine Poisnel; Farhana Oueslati; Martine Dhilly; Jérôme Delamare; Cécile Perrio; Danièle Debruyne; Louisa Barré

Book ID
116799213
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
375 KB
Volume
35
Category
Article
ISSN
0969-8051

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✍ John R. Lever; Chris M. Kinter; Hayden T. Ravert; John L. Musachio; William B. M 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 508 KB

## Abstract A delta opioid receptor antagonist, N1′‐methylnaltrindole (MeNTI), has been labeled with carbon‐11. The precursor for radiolabeling was prepared in 71% yield by benzylation of the phenolic moiety of naltrindole. Alkylation of the indole nitrogen using [^11^C]iodomethane and aqueous tetr