𝔖 Bobbio Scriptorium
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1163 The efficacy of oligonucleotide chip detecting YMDD mutants of hepatitis B virus in lamivudine-treated patients

✍ Scribed by HEO, J; CHO, M; KIM, G; KANG, D; SONG, G; YANG, U; JANG, H; PARK, H; KIM, C; KIM, H


Book ID
123290395
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
289 KB
Volume
38
Category
Article
ISSN
0270-9139

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## Abstract Chronic hepatitis B virus (CHBV) infection causes cirrhosis and hepatocellular carcinoma. Lamivudine (LAM) has been successfully used to treat CHBV infections but prolonged use leads to the emergence of drug‐resistant variants. This is primarily linked to a mutation in the tyrosine–meth