(11; 14) Translocation in three boys with acute lymphoblastic leukemia of T-cell immunophenotype
β Scribed by Harbott, J. ;Engel, R. ;Gerein, V. ;Schwamborn, D. ;Rudolph, R. ;Lampert, F.
- Publisher
- Springer-Verlag
- Year
- 1986
- Weight
- 808 KB
- Volume
- 52
- Category
- Article
- ISSN
- 1432-0584
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A workshop held by the "Groupe Frangais de Cytogenetique Hematologique" has identified a t ( I 0 I I)(p I 3-1 4;q 14-2 I) in four acute lyrnphoblastic leukemias of T-cell lineage. The immunophenotypes were consistent with immature thymocytes. This translocation is therefore a new candidate for a rec
The recurrent t(14;19)(q32;q13) translocation associated with chronic B-cell lymphoproliferative disorders, such as atypical chronic lymphocytic leukemia, results in the juxtaposition of the IGH@ and BCL3 genes and subsequent overexpression of BCL3. We report six patients with B-cell precursor acute
The t( 1014)(q24;ql I) is observed in the leukemia cells of 5-10% of cases of T-cell acute lymphoblastic leukemia (T-ALL). Recently, molecular analyses of a number of these translocations revealed simple reciprocal translocations between the T-cell receptor delta chain gene (TCRD) and a region of IO