𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1075 Differential expression of Parkin splice variant and wild type Parkin in sporadic Parkinson's disease


Book ID
122854152
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
248 KB
Volume
238
Category
Article
ISSN
0022-510X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The role of parkin in familial and spora
✍ Ted M. Dawson; Valina L. Dawson πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 122 KB πŸ‘ 1 views

## Abstract Mutations in parkin are the second most common known cause of Parkinson's disease (PD). Parkin is an ubiquitin E3 ligase that monoubiquitinates and polyubiquitinates proteins to regulate a variety of cellular processes. Loss of parkin's E3 ligase activity is thought to play a pathogenic

Wheel running and environmental enrichme
✍ M.S. Zajac; T.Y.C. Pang; N. Wong; B. Weinrich; L.S.K. Leang; J.M. Craig; R. Saff πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 656 KB

## Abstract Brain‐derived neurotrophic factor (BDNF) is an essential neurotrophin and regulation of its expression is complex due to multiple 5β€² untranslated exons which are separately spliced to a common coding exon to form unique mRNA transcripts. Disruption of BDNF gene expression is a key to th