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1070 Effects of the protease domain of hepatitis C virus NS3 protein on its helicase activity

✍ Scribed by RYPMA, R; LAM, A; FRICK, D

Book ID: 121888969
Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 129 KB
Volume: 38
Category: Article
ISSN: 0270-9139
DOI: 10.1016/S0270-9139(03)81108-4

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## Abstract Helicase motif VI is a short arginine-rich motif within the NTPase/helicase domain of the non-structural protein 3 (NS3) of the hepatitis C virus (HCV). We previously demonstrated that it reduces the catalytic activity and intracellular shuttling of protein kinase C (PKC). Thus, NS3-med