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Characterization of RNA Binding Activity and RNA Helicase Activity of the Hepatitis C Virus NS3 Protein

โœ Scribed by Yousang Gwack; Dong Wook Kim; Jang H. Han; Joonho Choe

Book ID
115578895
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
154 KB
Volume
225
Category
Article
ISSN
0006-291X

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โœ Koji Ishii; Yoshinobu Tanaka; Chan-Choo Yap; Hideki Aizaki; Yoshiharu Matsuura; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 271 KB

The nonstructural protein 5B (NS5B) of hepatitis C virus (HCV) is considered to possess RNA-dependent RNA polymerase (RdRp) activity and to play an essential role for the viral replication. In this study, we expressed the NS5B protein of 65 kd by a recombinant baculovirus. With the highly purified N