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1030 Somatic Hypermethylation of MSH2 is a Frequent Event in Lynch Syndrome Colorectal Cancers

✍ Scribed by Ajay Goel; Jennifer Rhees; Takeshi Nagasaka; C.R. Boland


Book ID
119431538
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
98 KB
Volume
138
Category
Article
ISSN
0016-5085

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CADM1/TSLC1 inactivation by promoter hyp
✍ Kequan Chen; Guanghai Wang; Liang Peng; Side Liu; Xiangsheng Fu; Yu Zhou; Haishe πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 410 KB

## Abstract Cell adhesion molecule 1 (CADM1/TSLC1), a putative tumor suppressor involving in cell adhesion, proliferation and apoptosis, is frequently inactivated in several carcinomas due to promoter hypermethylation. But alterations of CADM1/TSLC1 in colorectal carcinogenesis and clinical signifi