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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) disrupts social memory/recognition processes in the male mouse

✍ Scribed by Dean E. Dluzen; Jennifer D. Kreutzberg


Book ID
115804042
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
494 KB
Volume
609
Category
Article
ISSN
0006-8993

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## Abstract In 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) models of Parkinson's disease (PD), dopaminergic (DA) neurons have been shown to die by apoptosis. Moreover, recent postmortem and in vitro results have indicated that apoptotic cell death induced by 1‐methyl‐4‐phenylpyridinium (MPP