1-[2-Hydroxy-4-(3-methylbut-2-enyloxy)phenyl]ethan-1-one
✍ Scribed by Cheng, Die ;Liu, Mo ;Liu, Deng-Ke ;Liu, Ying ;Liu, Chang-Xiao
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 424 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The title compound, C~13~H~16~O~3~, is an intermediate in the synthesis of the anti-ulcer agent sofalcone. The asymmetric unit contains two independent molecules. Intramolecular O—H...O hydrogen bonds are formed between the carbonyl and hydroxyl groups.
📜 SIMILAR VOLUMES
View of the molecule of (I), showing the atom-labeling scheme. Displacement ellipsoids are drawn at the 30% probability level.
## Abstract 1‐[2‐hydroxy‐4‐(3‐sulfo‐1‐propyloxy)‐phenyl]‐3‐ ‐(3‐hydroxy‐4‐methoxyphenyl)‐propan‐1‐one sodium salt labelled with ^14^C at its carbonyl group (__1__) was synthetized starting from sodium acetate‐1‐^14^C through acetyl chloride‐1‐^14^C, resacetophenone‐carbonyl‐^14^C (__2__), 2‐hydroxy
In the title molecule, C~22~H~17~NO, the two approximately planar carbazole and phenyl groups make a dihedral angle of 45.34 (5)°. In the crystal structure, C—H...O hydrogen-bonded dimers are connected by additional C—H...O and C—H...π interactions into chains along the [001] direction.