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0-25. The incidence of BRCA1 and BRCA2 mutations in women with bilateral or early onset (under 35 years) breast cancer

✍ Scribed by M. Marafie; J. Kollias; K.M. Carpenter; A.L. Sharif; R.W. Blarney; G.S. Cross


Book ID
114317031
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
133 KB
Volume
6
Category
Article
ISSN
0960-9776

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BRCA1 and BRCA2 mutations in women with
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Germline mutations in BRCA1 and BRCA2 account for majority of hereditary breast and ovarian cancer. The complete coding sequence analysis of both genes was carried out in 197 breast/ovarian cancer patients from high-risk families and 53 patients with sporadic breast/ovarian cancer. In summary, 59 mu