δ-Aminolevulinic acid transport in Saccharomyces cerevisiae
✍ Scribed by Mariana Bermúdez Moretti; Susana Correa García; Carlos Stella; Eugenia Ramos; Alcira M.del C. Batlle
- Book ID
- 103118365
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 804 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0020-711X
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## Abstract A biosynthetic precursor of tetrapyrroles, δ‐aminolevulinic acid (ALA), can be formed via two pathways: enzymatic condensation of glycine and succinyl‐CoA by ALA synthase in animal mitochondria and some fungi, and the C~5~ pathway converting glutamate to ALA in plants, algae, archaea, a
The potential of protoporphyrin IX fluorescence induced by the systemic administration of delta-aminolevulinic acid (ALA) for the detection of tumours was tested in three different murine models (MS-2 fibrosarcoma, L1210 leukaemia, and Lewis lung carcinoma). Time-gated fluorescence images were acqui