cells expressing the ␥␦ T-cell receptor (TCR) display strong major histocompatibility complex (MHC)-unrestricted cytotoxicity against tumour cells when activated in vitro by interleukin 2 (IL-2) 1 . The cytotoxic activity of ␥␦ T cells is reminiscent of natural killer (NK) cells, which preferentiall
γδ T cells in autoimmunity
✍ Scribed by Yin, Zhinan ;Craft, Joe
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 679 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0344-4325
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In this work the suppressive activity of splenic T cells from young and aged BALB/c mice infected with Trypanosoma cruzi were compared and correlated with the development of autoimmune myocarditis. The T cells from young adult BALB/c mice with acute 7: cruzi infection exhibit suppressor activity whe
7~5 cells are attractive candidates for mediators of autoimmune disease. They can expand in germ-free mice, probably through recognition of autoantigens, and 7~5-cell-deficient mice, unlike mice deficient in a13 T cells or B cells, show no severe defects in the immune response to foreign antigen cha
~6 T cells consist of multiple lineages of cells with distinct antigen receptor repertoires, tissue localization and function. Recent evidence suggests that the ordered appearance of these sublineages during development is a result of programed rearrangement of Vy-gene segments. It appears that the