γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
✍ Scribed by Valdiglesias, Vanessa; Giunta, Simona; Fenech, Michael; Neri, Monica; Bonassi, Stefano
- Book ID
- 120201252
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 862 KB
- Volume
- 753
- Category
- Article
- ISSN
- 1383-5742
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## Abstract ## Purpose To evaluate the effects of the static magnetic field and typical imaging sequences of a high‐field magnetic resonance scanner (3 Tesla) on the induction of double‐strand breaks (DSBs) in two different human cell lines. ## Materials and Methods Human promyelocytic leukemia
## Abstract The measurement of γ‐H2AX foci induction in cells provides a sensitive and reliable method for the quantitation of DNA damage responses in a variety of cell types. Accurate and rapid methods to conduct such observations are desirable. In this study, we have employed the novel technique