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Induction and Repair of DNA Double-Strand Breaks in Human Cells: Dephosphorylation of Histone H2AX and its Inhibition by Calyculin A

✍ Scribed by Antonelli, Francesca; Belli, Mauro; Cuttone, Giacomo; Dini, Valentina; Esposito, Giuseppe; Simone, Giustina; Sorrentino, Eugenio; Tabocchini, Maria Antonella

Book ID: 120052571
Publisher: Bioone
Year: 2005
Tongue: English
Weight: 56 KB
Volume: 164
Category: Article
ISSN: 0033-7587
DOI: 10.1667/RR3379.1

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## Abstract The measurement of γ‐H2AX foci induction in cells provides a sensitive and reliable method for the quantitation of DNA damage responses in a variety of cell types. Accurate and rapid methods to conduct such observations are desirable. In this study, we have employed the novel technique