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βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

✍ Scribed by Xunshan Ding; Jamie Boney-Montoya; Bryn M. Owen; Angie L. Bookout; Katie Colbert Coate; David J. Mangelsdorf; Steven A. Kliewer

Book ID
119219195
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
870 KB
Volume
16
Category
Article
ISSN
1550-4131

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## Abstract Basic fibroblast growth factor (bFGF) is a heparinbinding protein, expressing potent mitogenic and angiogenic properties. Elevated levels of bFGF have been identified in human gliomas and glioma cell lines, suggesting that bFGF expression is involved in the aberrant growth patterns asso