β1,4-galactosyltransferase-I in synovial tissue of collagen-induced rat model of rheumatoid arthritis
✍ Scribed by Hairong Wang; Dawei Xu; Ran Tao; Xiaohui Ni; Aiguo Shen; Youhua Wang
- Book ID
- 106300506
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 537 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0372-8722
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## Abstract Glycosylation is one of the most important post‐translational modifications. It is clear that the single step of β‐1,4‐galactosylation is performed by a family of β‐1,4‐galactosyltransferases (β‐1,4‐GalTs), and that each member of this family may play a distinct role in different tissue
Production of antibodies to IgG and to type I and type I1 collagen (CI and CII) was analyzed by enzymelinked immunospot assay in patients with rheumatoid arthritis (RA) and patients with other inflammatory or degenerative joint diseases. Anti-CII-secreting cells, generally in high numbers, were foun