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β1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms

✍ Scribed by Véronique Bouchard; Charlène Harnois; Marie-Josée Demers; Sonya Thibodeau; Vincent Laquerre; Rémy Gauthier; Anne Vézina; Dominique Noël; Naoya Fujita; Takashi Tsuruo; Mélina Arguin; Pierre H. Vachon


Book ID
106349665
Publisher
Springer
Year
2008
Tongue
English
Weight
622 KB
Volume
13
Category
Article
ISSN
1360-8185

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✍ Charlène Harnois; Marie-Josée Demers; Véronique Bouchard; Karine Vallée; David G 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB 👁 2 views

To investigate the mechanisms responsible for survival and apoptosis/anoikis in normal human intestinal epithelial crypt cells, we analyzed the roles of various signaling pathways and cell adhesion on the expression of six Bcl-2 homologs (Bcl-2, Bcl-XL, Mcl-1, Bax, Bak, Bad) in the well established