𝔖 Bobbio Scriptorium
✦   LIBER   ✦

β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression

✍ Scribed by Barbara Bettegazzi; Marija Mihailovich; Alessandra Di Cesare; Alessandra Consonni; Romina Macco; Ilaria Pelizzoni; Franca Codazzi; Fabio Grohovaz; Daniele Zacchetti

Book ID
109028422
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
468 KB
Volume
33
Category
Article
ISSN
0953-816X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

IFN-γ-induced BACE1 expression is mediat
IFN-γ-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes
✍ Hyun Jin Cho; Su-Kyoung Kim; Seok Min Jin; Eun-Mi Hwang; Yong Sik Kim; Kyoon Huh 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 625 KB

## Abstract β‐Site APP cleaving enzyme 1 (BACE1) is an essential enzyme for the production of β amyloid. Since we found that injection of interferon‐γ (IFN‐γ) into young mouse brains increased BACE1 expression in astrocytes, we investigated molecular mechanisms underlying this process by cloning a