β-Lactam antibiotics: The first- and second-generation cephalosporins
✍ Scribed by Sahm, Daniel F.; Thornsberry, Clyde; Jones, Ronald N.
- Book ID
- 122868234
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 317 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0738-1751
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## Abstract Neue Cephalosporine, die in 3‐Stellung eine Fluormethylgruppe aufweisen (9, 17/Schema 1), wurden ausgehend von 2b unter Verwendung von 2‐Chlor‐1,1,2‐trifluor‐triäthylamin als Fluorierungsmittel hergestellt. Mit Piperidin‐schwefeltrifluorid erhielt man ferner aus 18 die 3‐Difluormethyl‐c