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β-Hydroxyisovalerylshikonin has a profound anti-growth activity in human endometrial and ovarian cancer cells

✍ Scribed by Noriyuki Takai; Tami Ueda; Masakazu Nishida; Kaei Nasu; Hisashi Narahara

Book ID: 113961480
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 968 KB
Volume: 109
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2007.12.020

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## Abstract The proteasome plays a pivotal role in the turnover of regulatory transduction proteins induced by activated cell membrane growth factor receptors. The epidermal growth factor receptor (EGFR) pathway is crucial in the development and progression of human epithelial cancers. Proteasome i