β-Glucosidase inhibitors incorporating pyridinium as a glucosyl mimic
✍ Scribed by Spencer Knapp; Yaohua Dong; Karen Rupitz; Stephen G. Withers
- Book ID
- 108038821
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 230 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The racemic 7‐oxanorbornanyl and norbornanyl aminoalcohols **3, 4, 42, 45**, and **46** were synthesized and tested as snail __β__‐mannosidase inhibitors. The amino tetraol **3** was obtained from the known sulfonyl acrylate **9** and furan **10**. Esterification provided **11** that un
A number of glycosidase inhibitors, some of them with promising biological properties, have been isolated or designed. Among them are not only polyhydroxylated piperidines (e.g. 1-deoxynojirimycin (2) [I], nojirimycin (3) [2], and related compounds), polyhydroxylated pyrrolidines (e.g. DAB 1 [3]) an