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β-Globin gene polymorphism in Saudis — triple Hpa I fragments

✍ Scribed by M. A. F. El-Hazmi; F. A. Jabbar; A. R. Al-Swailem; A. S. Warsy

Publisher
Springer
Year
1986
Tongue
English
Weight
274 KB
Volume
74
Category
Article
ISSN
0340-6717

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✦ Synopsis

In an attempt to investigate beta-globin gene polymorphism in the Saudi population, DNA samples were analysed using restriction endonucleases, Mst II and Hpa I. Both beta A and beta S genes showed extensive polymorphism and were found to be linked to 13.0 kb, 7.6 kb, 7.0 kb, and 5.6 kb Hpa I fragments. Three DNA samples out of a total of 436 analysed, had beta-globin gene linked to three Hpa I fragments of the sizes 13.0 kb, 7.6 kb, and 5.6 kb. In this paper we present our findings and discuss the possibility of multiple beta-globin loci.

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