β-Endorphin-like Peptide SLTCLVKGFY Is a Selective Agonist of Nonopioid β-Endorphin Receptor
✍ Scribed by E.V. Navolotskaya; T.A. Zargarova; N.V. Malkova; S.B. Krasnova; V.P. Zav'yalov; V.M. Lipkin
- Book ID
- 115589794
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 115 KB
- Volume
- 292
- Category
- Article
- ISSN
- 0006-291X
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Selective agonist of nonopioid beta-endorphin receptor decapeptide immunorphin (SLTCLVKGFY) was labeled with tritium (the specific activity of 24 Ci/mmol). [3H]Immunorphin was found to bind to nonopioid beta-endorphin receptor of mouse peritoneal macrophages (Kd = 2.0 +/- 0.1 nM). The [3H]immunorphi
Two selective agonists of nonopioid __β__‐endorphin receptor, synthetic peptides TPLVTLFK (octarphin) and SLTCLVKGFY (immunorphin), were labeled with tritium to specific activity of 29 and 25 Ci/mmol, respectively. Both labeled peptides were found to bind to high‐affinity naloxone‐insensitive bindin