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β-Endorphin 1–17 Modulates High Affinity IL-2 Receptor Expression on Human T Cells

✍ Scribed by ANNEMIEKE KAVELAARS; ANNETTE BEETSMA; JACOBIEN VON FRIJTAG DRABBE KÜNZEL; COBI J. HEIJNEN


Book ID
119867994
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
349 KB
Volume
650
Category
Article
ISSN
0890-6564

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The biological activities of IL-12 are mediated through a specific, high-affinity receptor composed of IL-12 receptor(R)beta1 and IL-12Rbeta2 subunits that exist primarily on T and NK cells. Remarkably, the expression of IL-12Rbeta2 on CD4(+) T cells in mouse and humans appears to be differentially