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Thymosin alpha 1 modulates the expression of high affinity interleukin-2 receptors on normal human lymphocytes

✍ Scribed by Kimberly D. Leichtling; Susana A. Serrate; Marcelo B. Sztein


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
876 KB
Volume
12
Category
Article
ISSN
0192-0561

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In this report, we have examined whether (6R)-tetrahydrobiopterin (H,biopterin) modulates the binding of interleukin 2 to high-affinity sites of the cloned mouse cytotoxic T-lymphocyte clone CTLL-2. Scatchard plot analysis of the equilibrium binding data reveals increased affinity when the cells are