Degradable Poly(β-amino ester) nanoparti
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Youqing Shen; Huadong Tang; Yihong Zhan; Edward A. Van Kirk; William J. Murdoch
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Article
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2009
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Elsevier Science
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English
⚖ 794 KB
Fast cytoplasmic drug delivery can overcome cancer cells' drug resistance and thus have an enhanced therapeutic efficacy. Such a drug delivery regime requires drug carriers capable of entering cancer cells, localizing and rapidly releasing the drug into endosomes/lysosomes, and subsequently disrupti