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β-Carbolines as agonistic or antagonistic benzodiazepine receptor ligands. 1. Synthesis of some 5-, 6- and 7-amino derivatives of 3-methoxycarbonyl-β-carboline (β-CCM) and of 3-ethoxycarbonyl-β-carboline (β-CCE)

✍ Scribed by Guido Settimj; Maria Rosaria Del Giudice; Rosella Ferretti; Franco Gatta


Book ID
112129051
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
603 KB
Volume
25
Category
Article
ISSN
0022-152X

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β-carbolines as benzodiazepine receptor
✍ Klaus P. Lippke; Walter E. Müller; Walter G. Schunack 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 564 KB

Numerous 0-carboline-3-carboxamides were synthesized by amidation of p-carboline-3-carboxylic acid, with various amino acids and amino acid esters serving as arnine components, and tested in respect to their affinity for the benzodiazepine receptor in mouse brain membranes. The title compounds have