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β-Alanine containing cyclic peptides with predetermined turned structure. V

✍ Scribed by Vincenzo Pavone; Angelina Lombardi; Michele Saviano; Benedetto Di Blasio; Flavia Nastri; Roberto Fattorusso; Ornella Maglio; Carla Isernia


Publisher
Wiley (John Wiley & Sons)
Year
1994
Tongue
English
Weight
900 KB
Volume
34
Category
Article
ISSN
0006-3525

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β-Alanine containing cyclic peptides wit
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## Abstract In the present paper we describe the synthesis, purification, single crystal x‐ray analysis, and nmr solution characterization, combined with restrained molecular dynamic simulations, of the cyclic hexapeptide __cyclo__‐(L‐Pro‐L‐Phe‐β‐Ala)~2~. The peptide was synthesized by classical so

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## Abstract In the present paper we describe the synthesis, purification, and single crystal x‐ray analysis of the cyclic pentapeptide __cyclo__‐(L‐Pro‐L‐Pro‐L‐Phe‐β‐Ala‐β‐Ala). The peptide was synthesized by classical solution methods and the cyclization of the free pentapeptide was accomplished i

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## Abstract In the present paper we describe the synthesis, purification, and single‐crystal x‐ray analysis of the cyclic tetrapeptide __cyclo__‐(L‐Pro‐L‐Phe‐β‐Ala‐β‐Ala). This compound contains the β‐alanyl‐β‐alanine dipeptide as putative cyclization arm to force the remaining dipeptide‐L‐Pro‐L‐Ph