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α,β-Dehydroamino Acids.

✍ Scribed by Christoph Bonauer; Thomas Walenzyk; Burkhard Koenig


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Synthesis of novel β-substituted α,β-deh
✍ Paula M.T Ferreira; Hernâni L.S Maia; Luı́s S Monteiro; Joana Sacramento 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 88 KB

b-Substituted a,b-dehydroamino acids are synthesised in high yields by a Michael addition of heterocyclic nucleophiles to the methyl esters of N-tert-butyloxycarbonyl,N-(4-toluenesulfonyl)dehydroamino acids, followed by a base-induced elimination of the 4-toluenesulfonyl group with regeneration of t