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α2U-Globulin: measurement in rat kidney and relationship to hyaline droplets

✍ Scribed by Michael D. Stonard; Peter G.N. Phillips; John R. Foster; Michael G. Simpson; Edward A. Lock


Book ID
115825379
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
507 KB
Volume
160
Category
Article
ISSN
0009-8981

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Quantitation of α2u-Globulin in Rat Kidn
✍ Axel Pähler; Kai Blumbach; Jörg Herbst; Wolfgang Dekant 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 147 KB

The renal accumulation of alpha2u-globulin has been implicated in the tumorigenicity of many nongenotoxic chemicals to the kidney of the male rat. Several chemicals inducing renal tumors in the male rat were shown to bind to alpha2u-globulin. This binding impairs the renal degradation of alpha2u-glo