𝔖 Bobbio Scriptorium
✦   LIBER   ✦

α - synuclein and Parkinson's disease: the first roadblock

✍ Scribed by Christelle En Lin Chua; Bor Luen Tang


Book ID
119983447
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2006
Tongue
English
Weight
169 KB
Volume
10
Category
Article
ISSN
1582-1838

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Parkinson's disease and α-synuclein expr
✍ Michael J. Devine; Katrina Gwinn; Andrew Singleton; John Hardy 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB

## Abstract Genetic studies of Parkinson's disease over the last decade or more have revolutionized our understanding of this condition. α‐Synuclein was the first gene to be linked to Parkinson's disease, and is arguably the most important: the protein is the principal constituent of Lewy bodies, a

Methionine oxidation, α-synuclein and Pa
✍ Charles B. Glaser; Ghiam Yamin; Vladimir N. Uversky; Anthony L. Fink 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 419 KB

The aggregation of normally soluble a-synuclein in the dopaminergic neurons of the substantia nigra is a crucial step in the pathogenesis of Parkinson's disease. Oxidative stress is believed to be a contributing factor in this disorder. Because it lacks Trp and Cys residues, mild oxidation of a-synu