(−)-α-Isosparteine as a chiral ligand in asymmetric allylic alkylation
✍ Scribed by Jahyo Kang; Won Oh Cho; Hyung^Geun Cho
- Book ID
- 108036230
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 359 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate (8a) with a dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of novel chiral phosphine-oxazinane ligands such as 5b in good yields with good enantioselectivities (up to 95% ee).
## Abstract A family of monodentate polystyrene‐supported phosphites, phosphoramidites and phosphanes has been prepared and evaluated as ligands in rhodium‐catalysed asymmetric hydrogenation and palladium‐catalysed asymmetric allylic alkylation. The supported ligands yielded active and enantioselec