𝔖 Bobbio Scriptorium
✦   LIBER   ✦

α-Hydroxylation at C-15 and C-16 in Cholesterol: Synthesis of (25 R )-5α-Cholesta-3β,15α,26-triol and (25 R )-5α-Cholesta-3β,16α,26-triol from Diosgenin

✍ Scribed by Williams, John R.; Gong, Hua; Hoff, Nathan; Olubodun, Olaoluwa I.; Carroll, Patrick J.


Book ID
127138721
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
70 KB
Volume
6
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


ChemInform Abstract: Synthesis of (25R)-
✍ I. IZZO; F. DE RICCARDIS; G. SODANO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

Synthesis of (25R)-5α- 6β,15α,16β, a Cytostatic Starfish Steroid. -The title steroid (VII) is synthesized from diosgenin (I). The key step is the oxidation of the enolsilane (IV) with dimethyldioxirane to introduce the 15α-hydroxy group. -(IZZO, I.; DE

Inhibitors of sterol synthesis. Chemical
✍ Shankar Swaminathan; Frederick D. Pinkerton; William K. Wilson; George J. Schroe 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 570 KB

(25R)-5 alpha-Cholest-8(14)-ene-3 beta,15 beta,26-triol (III) was prepared by reduction of (25R)-3 beta,26-diacetoxy-5 alpha-cholest-8(14)-en-15-one with sodium borohydride followed by treatment of the crude product with lithium aluminium hydride. The trihydroxysterol III, a potential metabolite of