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α-Fetoprotein promoter-targeted sodium iodide symporter gene therapy of hepatocellular carcinoma

✍ Scribed by Willhauck, M J; Sharif Samani, B R; Klutz, K; Cengic, N; Wolf, I; Mohr, L; Geissler, M; Senekowitsch-Schmidtke, R; Göke, B; Morris, J C


Book ID
110040101
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
226 KB
Volume
15
Category
Article
ISSN
0969-7128

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For an approach of gene therapy for hepatocellular carcinoma (HCC), transcriptional regulatory sequence (TRS) of either alpha-fetoprotein (AFP) or albumin has been used for targeting cancer cells. To examine the feasibility of using TRSs of these genes for possible gene therapy of HCCs, the cellular