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Über einige β-substituierte Fettsäureamide mit lokalanästhetischer Wirkung. 5. Mitteilung

✍ Scribed by A. E. Wilder Smith

Publisher
John Wiley and Sons
Year
1959
Tongue
German
Weight
407 KB
Volume
42
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A further series of butyric acid amides has been synthesised in which the diethylamino, pyrrolidino and piperidino groups of previously reported syntheses have been substituted by morpholino groups. The influence of the various groups in the present and in previously reported derivatives on the pharmacology of the series is reported and summarised. The conditions necessary for maximum local anaesthesia and barbiturate potentiation are discussed.

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