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Über einige β-substituierte Fettsäureamide mit lokalanästhetischer Wirkung. 4. Mitteilung

✍ Scribed by A. E. Wilder Smith

Publisher
John Wiley and Sons
Year
1959
Tongue
German
Weight
343 KB
Volume
42
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The preparation and properties of some new β‐alkylamino‐butyric anilides have been described and a summary report on some of their pharmacological properties is given. Two derivatives (the p‐(carbo‐n‐butoxy)‐anilides of β‐diethylamino‐ and of β‐(1‐piperidino)‐ butyric acid = XVI and XVIII) show promise as very active local anaesthetics with low toxicities. One derivative (β‐N‐pyrrolidino‐n‐butyric acid anilide = XXVII) shows strong potentiation of the sedative properties of barbiturates.

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