Zur Synthese von 1bzw. 2-Methyl(Benzyl)-6,7-dihydro-6-0x0-pyrazolo [3,4-b] pyridinen 1-Substituierte 3-(11) bzw. 5-Amino-pyrazole (111) liefern mit Acetessigester (I, R' = Me oder E t ) N-(Pyrazoly1)-acetessigsaureamide (IV) (A) oder (1-Methyl-2-alkoxycarbonyl-viny1amino)pyrazole (V bzw. VI) (B). Re
Über 6,7-Dihydro-4-methyl-6-oxo-2- und -1-phenyl-pyrazolo [3,4-b] pyridin
✍ Scribed by Helmut Dorn; Rüdiger Ozegowski
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 303 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0044-2402
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The title compound, C 20 H 15 FN 4 O, was synthesized by the reaction of 5-amino-3-methyl-1-phenylpyrazole with ethyl 2cyano-3-(4-fluorophenyl)-1-acylate in glycol under microwave irradiation. The tetrahydropyridine ring adopts a distorted envelope conformation. The pyrazole ring forms a dihedral an
Single-crystal X-ray study T = 193 K Mean '(C±C) = 0.002 A Ê R factor = 0.041 wR factor = 0.103 Data-to-parameter ratio = 12.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C 19 H 16 BrN 3 O, was synthesized by the reaction of 5-amino-3-methyl-1-phenylpyrazole with 4-bromophenylaldehyde and Medrum's acid in glycol under microwave irradiation. X-ray crystal structure analysis reveals three crystallographically independent molecules in the asymmetric