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Zur Mutagenität des INH

✍ Scribed by Kehler, E. ;Röhrborn, G. ;Propping, P. ;Buselmaier, W.

Book ID
105467180
Publisher
Springer-Verlag
Year
1973
Weight
322 KB
Volume
148
Category
Article
ISSN
0033-4073

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✍ W. Dedek; H. Scheufler; G. W. Fischer 📂 Article 📅 1975 🏛 Springer-Verlag 🌐 English ⚖ 304 KB

After i.p. administration to AB mice of 405 mg/kg desmethyltrichlorphone (sodium salt) in a single dose and 54 mg/kg daily for 3 weeks, the mutagenic effect in the dominant lethal test was at least the same as that of trichlorphone. these findings indicate that the genotoxic effect of trichlorphone