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Zur Mutagenität von Desmethyl-Trichlorphon im Dominanten-Letal-Test an der Hausmaus

✍ Scribed by W. Dedek; H. Scheufler; G. W. Fischer


Book ID
104736199
Publisher
Springer-Verlag
Year
1975
Tongue
English
Weight
304 KB
Volume
33
Category
Article
ISSN
0340-5761

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✦ Synopsis


After i.p. administration to AB mice of 405 mg/kg desmethyltrichlorphone (sodium salt) in a single dose and 54 mg/kg daily for 3 weeks, the mutagenic effect in the dominant lethal test was at least the same as that of trichlorphone. these findings indicate that the genotoxic effect of trichlorphone is not likely to be due to its alkylating properties.