## Abstract Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between 4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited osteogenesis, while chondrogenesis is unaffected. The reasons for these results may be associated with the inheren
ZNF 281 decides the early differentiation fate of human mesenchymal stem cells
β Scribed by Kwang-won Seo; Seon-Kyung Lee; Dilli Ram Bhandari; Sang-Bum Park; Kyung-Hwan Roh; Se-Ran Yang; Kyung-Sun Kang
- Book ID
- 113955261
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 49 KB
- Volume
- 356
- Category
- Article
- ISSN
- 0012-1606
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Noggin is a secreted protein that inhibits the binding of bone morphogenetic proteins (BMPs) to their cognate receptor. Its role in human mesenchymal stem cell differentiation has not been well studied. Here, we studied the effect of noggin on human mesenchymal stem cell differentiation
## Abstract Copper plays important functional roles in bone metabolism and turnover. It is known that it is essential for normal growth and development of the skeleton in humans and in animals. Although at present the exact role that copper plays in bone metabolism is unknown, bone abnormalities ar