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Basal Autophagy Decreased During the Differentiation of Human Adult Mesenchymal Stem Cells

✍ Scribed by Oliver, Lisa; Hue, Erika; Priault, Muriel; Vallette, François M.

Book ID
120069073
Publisher
Mary Ann Liebert
Year
2012
Tongue
English
Weight
687 KB
Volume
21
Category
Article
ISSN
1547-3287

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## Abstract Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between 4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited osteogenesis, while chondrogenesis is unaffected. The reasons for these results may be associated with the inheren